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DSPE-PEG-Hydrazide, DSPE-PEG-HZ, Phospholipid-Polyethylene Glycol-Hydrazide MW: 1000

2022-08-09 16:02:00 【XYBMWCR】

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Product Description:

Chinese: Phospholipid-polyethylene glycol-hydrazide (MW: 1000)

English: DSPE-PEG-Hydrazide, DSPE-PEG-HZ

DSPE-PEG hydrazide is a carbonyl-reactive phospholipid PEG derivative that can react with aldehyde or ketone groups derived from polysaccharides or glycoproteins.DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is a highly hydrophobic 18-carbon phospholipid.On the other hand, the PEG backbone has good hydrophilicity and water solubility.Hydrazides easily react with aldehyde groups to form stable hydrogen bonds, which are more stable than Schiff bases formed between aldehyde groups and amine groups.The reaction between hydrazides and aldehydes allows for the rapid and efficient conjugation of phospholipids to carbohydrates, glycoproteins, antibodies, and enzymes.The PEG linker between DSPE and hydrazide has better water solubility, flexible link structure and enhanced stability.