DSPE-PEG-PDP, DSPE-PEG-OPSS, phospholipid-polyethylene glycol-mercaptopyridine reduce the immunogenicity of peptides

Parameters of phospholipid-polyethylene glycol-mercaptopyridine (MW: 1000):

DSPE-PEG-OPSS description:

DSPE-PEG-PDP is an active phospholipid PEG derivative that can react with free sulfhydryl groups.DSPE (1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is a highly hydrophobic 18-carbon phospholipid.On the other hand, the PEG backbone has good hydrophilicity and water solubility.PDP (pyridyl disulfide) functionalized DSPE-PEG can react with free sulfhydryl groups to form disulfide bonds, which can be cleaved by DTT or other disulfide bond reducing reagents.The reaction between PDP and thiol allows the efficient attachment of DSPE-PEG to thiol-containing molecules or particles.

Phospholipid PEG mercaptopyridine (DSPE-PEG-OPSS) can be used to modify proteins, peptides and other materials with reactive groups.Phospholipid (-DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol with hydrophilic and hydrophobic properties.PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides.It also inhibits the non-specific binding of charged molecules on the modified surface.

Product related:

Iodoacetyl-polyethylene glycol-silane, IA-PEG-Silane, MW: 5000

Eight-Arm-Polyethylene Glycol-Chloride, 8-Arm PEG-Cl, MW: 3400

Four-arm-polyethylene glycol-chloride, 4-Arm PEG-Cl, MW: 2000

Tetrazine-PEG-Sulfhydryl, Tetrazine-PEG-SH, MW: 10000

phospholipid-polyethylene glycol-fluorescein, DSPE-PEG-FITC, MW: 20000

phospholipid-polyethylene glycol-maleimide, DSPE-PEG-MAL, MW: 1000

Dimyristoylphosphatidylethanolamine-polyethylene glycol-maleimide, DMPE-PEG-Mal, MW: 3400

Methoxy polyethylene glycol lysine maleimide dibenzocyclooctyne, mPEG-Lys(MAL)-DBCO, MW: 5000

The above information about DSPE-PEG-PDP is provided by Shaanxi Xinyan Bomei Biotechnology Co., Ltd. Z, please consult for details